Telomerase RNA component

Ciliate telomerase RNA
Ciliate telomerase RNA
Identifiers
Symbol	Telomerase-cil
Rfam	RF00025
Other data
RNA type	Gene
Domain	Eukaryote
PDB structures	PDBe

Vertebrate telomerase RNA
Vertebrate telomerase RNA
Identifiers
Symbol	Telomerase-vert
Rfam	RF00024
Other data
RNA type	Gene
Domain(s)	Eukaryote; Virus
PDB structures	PDBe

TERC
	TERC cristallised (PDB 1YMO)
Identifiers
Aliases	TERC, DKCA1, PFBMFT2, SCARNA19, TR, TRC3, hTR, Telomerase RNA component, TER
External IDs	OMIM: 602322; GeneCards: TERC
Gene location (Human)
Chr.	Chromosome 3 (human)
End	169,765,047 bp
RNA expression pattern
	Top expressed in
	bone marrow cell; ; epithelium of colon; ; testicle; ; skeletal muscle tissue; ; sural nerve; ; Achilles tendon; ; tonsil; ; lung; ; kidney; ; blood;
	n/a
	More reference expression data
	n/a
Orthologs
Databases	NCBI: entry; OMA: entry
	7012
	n/a
	ENSG00000277925
	n/a
	n; a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

Saccharomyces cerevisiae telomerase RNA

Identifiers
Symbol	Sacc_telomerase
Rfam	RF01050
Other data
RNA type	Gene
Domain	Eukaryote
PDB structures	PDBe

Telomerase RNA component (TERC), also abbreviated TER or TR, is a non-coding RNA found in eukaryotes that is a component of the telomerase enzyme, which extends telomeres at the ends of linear chromosomes. TERC folds into a complex secondary structure which binds to and interacts with TERT, the protein component of telomerase, and serves as the RNA template for the reverse transcription reaction catalyzed by TERT. Telomerase RNAs differ greatly in length, sequence and structure between vertebrates, ciliates and yeasts, but they share a 5' pseudoknot structure close to the template sequence; vertebrate telomerase RNAs also share a 3' H/ACA snoRNA-like domain.