SimThyr

SimThyr
SimThyr 3.1 on openSUSE 11
Original authors	Johannes W. Dietrich, Ulla Mitzdorf, Renate Pickardt, Rudolf Hoermann, John E. M. Midgley
Developer	Ruhr University Bochum
Release	2002 (2002)
Stable release	4.0.6 / April 23, 2022 (2022-04-23)
Written in	Pascal and Object Pascal
Operating system	macOS, Windows and Linux
Platform	PowerPC, IA-32, x86-64 and ARM, m68k (legacy versions only)
Available in	British English, German (SimThyr 2.0 or older only)
Type	Free scientific application software for physiological simulations
License	BSD-style
Website	simthyr.sourceforge.net
Repository	sourceforge.net/p/simthyr/code/HEAD/tree/

SimThyr is a free continuous dynamic simulation program for the pituitary-thyroid feedback control system. The open-source program is based on a nonlinear model of thyroid homeostasis. In addition to simulations in the time domain the software supports various methods of sensitivity analysis. Its simulation engine is multi-threaded and supports multiple processor cores. SimThyr provides a GUI, which allows for visualising time series, modifying constant structure parameters of the feedback loop (e.g. for simulation of certain diseases), storing parameter sets as XML files (referred to as "scenarios" in the software) and exporting results of simulations in various formats that are suitable for statistical software. SimThyr is intended for both educational purposes and in-silico research.