Persulfide

Cysteine hydropersulfide (top) and glutathione hydropersulfide (bottom), the two most physiologically relevant persulfide species. The additional sulfanyl group is marked in orange.

In chemistry, hydropersulfide refers to the functional group R-S-S-H. The anionic form of a hydropersulfide is a persulfide, analogous to the nomenclature for hydroperoxides. Persulfides are intermediates in the biosynthesis of iron-sulfur proteins and are invoked as precursors to hydrogen sulfide, a biological signaling molecule. Hydropersulfides are thought to mediate many of the antioxidant signaling functions once ascribed purely to hydrogen sulfide via modification of protein cysteine (Cys) residues in a process referred to as persulfidation. Hydropersulfides are prototypical reactive sulfur species.

This page is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.