Papain
| Papain family cysteine protease | |||||||
|---|---|---|---|---|---|---|---|
 Papain from Carica papaya | |||||||
| Identifiers | |||||||
| Symbol | Peptidase_C1 | ||||||
| Pfam | PF00112 | ||||||
| InterPro | IPR000668 | ||||||
| PROSITE | PDOC00126 | ||||||
| SCOP2 | 1aec / SCOPe / SUPFAM | ||||||
| |||||||
| papain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.22.2 | ||||||||
| CAS no. | 9001-73-4 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea cundinamarcensis). It is the namesake member of the papain-like protease family.
It has wide ranging commercial applications in the leather, cosmetic, textiles, detergents, food and pharmaceutical industries. In the food industry, papain is used as an active ingredient in many commercial meat tenderizers.