Peroxisome proliferator-activated receptor

PPAR -alpha and -gamma pathways. Abbreviation: RXR, retinoid X receptor.

In the field of molecular biology, the peroxisome proliferator–activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating gene expression. PPARs play essential roles in regulating cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis