Period circadian protein homolog 1

PER1
Identifiers
Aliases	PER1, PER, RIGUI, hPER, period circadian clock 1, period circadian regulator 1
External IDs	OMIM: 602260; MGI: 1098283; GeneCards: PER1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1UL6
Gene location (Human) Chr. Chromosome 17 (human) Band 17p13.1 Start 8,140,472 bp End 8,156,506 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B3 Start 68,986,043 bp End 69,000,786 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastric mucosa tibial nerve skin of leg skin of abdomen right ovary left ovary tibial arteries right lung left uterine tube anterior pituitary Top expressed in granulocyte muscle of thigh superior frontal gyrus plantaris muscle extensor digitorum longus muscle neural layer of retina lacrimal gland ankle primary visual cortex stroma of bone marrow More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transcription factor binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding E-box binding kinase binding chromatin DNA binding ubiquitin protein ligase binding protein binding transcription corepressor binding Cellular component cytoplasm nucleus nucleoplasm cytosol Biological process histone H3 deacetylation negative regulation of glucocorticoid receptor signaling pathway regulation of transcription, DNA-templated response to light stimulus regulation of cytokine production involved in inflammatory response regulation of sodium ion transport rhythmic process negative regulation of transcription by RNA polymerase II negative regulation of I-kappaB kinase/NF-kappaB signaling circadian regulation of gene expression transcription, DNA-templated entrainment of circadian clock negative regulation of JNK cascade circadian regulation of translation regulation of circadian rhythm circadian rhythm histone H3 acetylation regulation of hair cycle histone H4 acetylation posttranscriptional regulation of gene expression response to cAMP regulation of p38MAPK cascade negative regulation of transcription, DNA-templated entrainment of circadian clock by photoperiod positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 5187 18626 Ensembl ENSG00000179094 ENSMUSG00000020893 UniProt O15534 O35973 RefSeq (mRNA) NM_002616 NM_001159367 NM_011065 RefSeq (protein) NP_002607 NP_001152839 NP_035195 Location (UCSC) Chr 17: 8.14 – 8.16 Mb Chr 11: 68.99 – 69 Mb PubMed search
Wikidata
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Period circadian protein homolog 1 is a protein in humans that is encoded by the PER1 gene.