ORC1

ORC1
Identifiers
Aliases	ORC1, HSORC1L, PARC1, origin recognition complex subunit 1
External IDs	OMIM: 601902; MGI: 1328337; GeneCards: ORC1
Gene location (Human) Chr. Chromosome 1 (human) Band 1p32.3 Start 52,372,829 bp End 52,404,423 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 C7 Start 108,436,620 bp End 108,472,030 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle ventricular zone gonad ganglionic eminence bone marrow mucosa of transverse colon secondary oocyte rectum stromal cell of endometrium bone marrow cell Top expressed in zygote secondary oocyte primary oocyte epiblast tail of embryo genital tubercle primitive streak embryo embryo blastocyst More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding nucleotide binding chromatin binding protein binding ATP binding DNA replication origin binding metal ion binding Cellular component nuclear origin of replication recognition complex plasma membrane nucleolus origin recognition complex nucleus nucleoplasm cytosol Biological process G1 phase DNA replication regulation of transcription involved in G1/S transition of mitotic cell cycle DNA replication initiation G1/S transition of mitotic cell cycle mitotic cell cycle mitotic DNA replication checkpoint signaling Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 4998 18392 Ensembl ENSG00000085840 ENSMUSG00000028587 UniProt Q13415 Q9Z1N2 RefSeq (mRNA) NM_001190818 NM_001190819 NM_004153 NM_001014425 NM_011015 RefSeq (protein) NP_001177747 NP_001177748 NP_004144 NP_035145 Location (UCSC) Chr 1: 52.37 – 52.4 Mb Chr 4: 108.44 – 108.47 Mb PubMed search
Wikidata
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Origin recognition complex subunit 1 is a protein that in humans is encoded by the ORC1 gene. It is closely related to CDC6, and both are the same protein in archaea.