MALAT1

Conserved secondary structure in Metastasis associated lung adenocarcinoma transcript 1
Conserved secondary structure in Metastasis associated lung adenocarcinoma transcript 1
	Predicted secondary structure and sequence conservation of MALAT1
Identifiers
Symbol	MALAT1
Rfam	RF01871
Other data
RNA type	Gene;
Domain	Eukaryota;
GO	GO:2000147
SO	SO:0001263
PDB structures	PDBe

MALAT1
Identifiers
Aliases	MALAT1, HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO2853, mascRNA, metastasis associated lung adenocarcinoma transcript 1 (non-protein coding), metastasis associated lung adenocarcinoma transcript 1
External IDs	OMIM: 607924; GeneCards: MALAT1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	65,506,516 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; trigeminal ganglion; ; cardia; ; corpus callosum; ; pylorus; ; seminal vesicula; ; Achilles tendon; ; external globus pallidus; ; spinal ganglia; ; pars compacta;
	n/a
	More reference expression data
	n/a
Orthologs
Databases	NCBI: entry; OMA: entry
	378938
	n/a
	ENSG00000251562
	n/a
	n; a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1) also known as NEAT2 (Nuclear-Enriched Abundant Transcript 2) is an infrequently spliced long non-coding RNA, which is highly conserved amongst mammals and highly expressed in the nucleus. It regulates the expression of metastasis-associated genes. It also positively regulates cell motility via the transcriptional and/or post-transcriptional regulation of motility-related genes. MALAT1 may play a role in temperature-dependent sex determination in the Red-eared slider turtle (Trachemys scripta).