KCNK4

KCNK4
Identifiers
Aliases	KCNK4, K2p4.1, TRAAK, TRAAK1, potassium two pore domain channel subfamily K member 4, FHEIG
External IDs	OMIM: 605720; MGI: 1298234; GeneCards: KCNK4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3UM7, 4I9W, 4RUE, 4RUF, 4WFE, 4WFF, 4WFG, 4WFH
Gene location (Human)
Chr.	Chromosome 11 (human)
End	64,300,031 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	6,911,883 bp
RNA expression pattern
	Top expressed in
	nucleus accumbens; ; temporal lobe; ; amygdala; ; hippocampus proper; ; superior frontal gyrus; ; prefrontal cortex; ; anterior cingulate cortex; ; right frontal lobe; ; dorsolateral prefrontal cortex; ; caudate nucleus;
	Top expressed in
	primary visual cortex; ; morula; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; lip; ; entorhinal cortex; ; intestinal villus; ; esophagus; ; Ileal epithelium; ; CA3 field;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	potassium channel activity; mechanosensitived potassium channel activity; voltage-gated ion channel activity; temperature-gated cation channel activity; potassium ion leak channel activity; identical protein binding;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; potassium channel complex;
Biological process	sensory perception of temperature stimulus; regulation of ion transmembrane transport; cellular response to alkaline pH; memory; ion transport; cellular response to temperature stimulus; potassium ion transport; cellular response to mechanical stimulus; cellular response to fatty acid; potassium ion transmembrane transport; sensory perception of pain; detection of mechanical stimulus involved in sensory perception of touch; stabilization of membrane potential;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	50801
	16528
	ENSG00000182450
	ENSMUSG00000024957
	Q9NYG8
	O88454
	NM_016611; NM_033310; NM_001317090
	NM_008431
	NP_001304019; NP_201567
	NP_032457
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium channel subfamily K member 4 is a protein that in humans is encoded by the KCNK4 gene. KCNK4 protein channels are also called TRAAK channels.