Intestinal gland

Intestinal gland
Micrograph of the small intestine mucosa showing the intestinal glands - bottom 1/3 of image. H&E stain.
Details
Identifiers
Latinglandula intestinalis
TA98A05.6.01.012
A05.7.01.008
TA22942, 2969
FMA63621 15052, 63621
Anatomical terminology

In histology, an intestinal gland (also crypt of Lieberkühn and intestinal crypt) is a gland found in between villi in the intestinal epithelial lining of the small intestine and large intestine (or colon). The glands and intestinal villi are covered by epithelium, which contains multiple types of cells: enterocytes (digesting and absorbing nutrients and electrolytes), goblet cells (secreting mucus), enteroendocrine cells (secreting hormones), cup cells, tuft cells, and at the base of the gland, Paneth cells (secreting anti-microbial peptides) and intestinal stem cells. Underlying the epithelium of the crypts and villi is the lamina propria, which contains various stromal cells including fibroblasts, myofibroblasts, telocytes, vascular and lymphatic capillaries, and leukocytes.