Interstate 265
 Interstate 265/Indiana SR 265/Kentucky 841 | ||||||||||
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| Gene Snyder Freeway (Kentucky); Lee H. Hamilton Freeway (Indiana) | ||||||||||
I-265 (signed) highlighted in red; signed as KY 841 in cyan; signed as IN 265 in blue; non-concurrent KY 841 in purple | ||||||||||
| Route information | ||||||||||
| Auxiliary route of I-65 | ||||||||||
| Maintained by INDOT and KYTC | ||||||||||
| Length | 31.21 mi (50.23 km) | |||||||||
| Existed | 1977–present | |||||||||
| Component highways |  I-265 from New Albany, IN to Louisville, KY KY 841 in Louisville, KY | |||||||||
| Restrictions | No hazardous goods on Lewis and Clark Bridge and East End Tunnel | |||||||||
| Major junctions | ||||||||||
| Beltway around Louisville, KY | ||||||||||
| Counterclockwise end |  I-64 / US 150 / SR 62 near New Albany, IN | |||||||||
| I-65 near Jeffersonville, IN I-71 in Louisville, KY I-64 in Louisville, KY I-65 in Louisville, KY | ||||||||||
| Clockwise end | US 31W / US 60 / KY 1934 in Louisville, KY | |||||||||
| Location | ||||||||||
| Country | United States | |||||||||
| States | Kentucky, Indiana | |||||||||
| Counties | KY: Jefferson IN: Clark, Floyd | |||||||||
| Highway system | ||||||||||
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Interstate 265 (I-265) is a 31.21-mile (50.23 km) Interstate Highway partially encircling the Louisville metropolitan area. Starting from I-65 in the southern part of Louisville, it runs through Jefferson County, Kentucky, crosses the Ohio River on the Lewis and Clark Bridge into Indiana, meets I-65 for a second time, and then proceeds westbound to terminate at the I-64 interchange.
The entire Kentucky stretch of the road is cosigned with Kentucky Route 841 (KY 841). An additional 10.25-mile-long (16.50 km) stretch of freeway between U.S. Route 31W (US 31W)/US 60/KY 1934 and I-65 in southern Louisville is solely designated as KY 841. The portion from I-71 to the Ohio River, while designated as I-265 by AASHTO, is only signed as KY 841. The highway is named the Gene Snyder Freeway (originally named the Jefferson Freeway), after the former congressman from Kentucky, and usually called "the Snyder" by locals.
Likewise on the Indiana side, the stretch from I-65 to the bridge, while designated as I-265 is signed as State Route 265 (SR 265). The highway is known as the Lee H. Hamilton Freeway after the former congressman from Indiana.
I-265 signage for the section from I-71 to the Indiana I-65 interchange will be replaced by October 2026, when the mileage and exit numbering will be reversed, with mileage and exit numbers increasing from the Indiana/Kentucky border at the Ohio River to the terminus at I-64.