GroES

Available protein structures:
PDB	IPR020818 PF00166 (ECOD; PDBsum)
AlphaFold	IPR020818; PF00166;

Cpn10
Cpn10
	gp31 co-chaperonin from bacteriophage t4
Identifiers
Symbol	Cpn10
Pfam	PF00166
Pfam clan	CL0296
InterPro	IPR020818
PROSITE	PDOC00576
SCOP2	1lep / SCOPe / SUPFAM
PDB
Available protein structures:
PDB	IPR020818 PF00166 (ECOD; PDBsum)
AlphaFold	IPR020818; PF00166;

HSPE1
Identifiers
Aliases	HSPE1, heat shock 10kDa protein 1, CPN10, EPF, GROES, HSP10, heat shock protein family E (Hsp10) member 1
External IDs	OMIM: 600141; MGI: 104680; GeneCards: HSPE1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4PJ1
Gene location (Human)
Chr.	Chromosome 2 (human)
End	197,503,449 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	55,130,466 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; mucosa of transverse colon; ; right lobe of liver; ; hypothalamus; ; human kidney; ; ventricular zone; ; C1 segment;
	Top expressed in
	embryo; ; embryo; ; yolk sac; ; right kidney; ; epiblast; ; blastocyst; ; ventricular zone; ; abdominal wall; ; migratory enteric neural crest cell; ; neural tube;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	chaperone binding; protein binding; ATP binding; metal ion binding; unfolded protein binding; RNA binding;
Cellular component	cytoplasm; extracellular exosome; membrane; mitochondrion; mitochondrial matrix;
Biological process	response to unfolded protein; activation of cysteine-type endopeptidase activity involved in apoptotic process; protein folding; osteoblast differentiation; chaperone cofactor-dependent protein refolding;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	3336
	15528
	ENSG00000115541
	ENSMUSG00000073676
	P61604
	Q64433
	NM_002157
	NM_008303
	NP_002148
	NP_032329
	Wikidata
View/Edit Human	View/Edit Mouse

Heat shock 10 kDa protein 1 (Hsp10), also known as chaperonin 10 (cpn10) or early-pregnancy factor (EPF), is a protein that in humans is encoded by the HSPE1 gene. The homolog in E. coli is GroES that is a chaperonin which usually works in conjunction with GroEL.