GTF2F1

GTF2F1
Identifiers
Aliases	GTF2F1, general transcription factor IIF, polypeptide 1, 74kDa, BTF4, RAP74, TF2F1, TFIIF, general transcription factor IIF subunit 1
External IDs	OMIM: 189968; MGI: 1923848; GeneCards: GTF2F1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1F3U, 1I27, 1J2X, 1NHA, 1ONV, 2K7L, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Gene location (Human) Chr. Chromosome 19 (human) Band 19p13.3 Start 6,379,572 bp End 6,393,981 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17|17 D Start 57,310,405 bp End 57,318,288 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellum cerebellar cortex cerebellar hemisphere left testis right hemisphere of cerebellum right testis left ovary prefrontal cortex anterior pituitary superior frontal gyrus Top expressed in saccule otic placode otic vesicle seminiferous tubule neural layer of retina tail of embryo primitive streak primary oocyte yolk sac genital tubercle More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding transcription coactivator activity transcription factor binding protein binding phosphatase activator activity RNA binding protein phosphatase binding protein domain specific binding RNA polymerase II general transcription initiation factor activity promoter-specific chromatin binding Cellular component intracellular membrane-bounded organelle nucleoplasm transcription factor TFIIF complex cell junction transcription factor TFIID complex nucleus protein-containing complex Biological process mRNA splicing, via spliceosome regulation of transcription, DNA-templated transcription elongation from RNA polymerase II promoter response to virus 7-methylguanosine mRNA capping transcription by RNA polymerase II transcription, DNA-templated positive regulation of viral transcription transcription initiation from RNA polymerase II promoter positive regulation of transcription elongation from RNA polymerase II promoter positive regulation of transcription by RNA polymerase II snRNA transcription by RNA polymerase II fibroblast growth factor receptor signaling pathway positive regulation of catalytic activity RNA metabolic process negative regulation of protein binding Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 2962 98053 Ensembl ENSG00000125651 ENSMUSG00000002658 UniProt P35269 Q3THK3 RefSeq (mRNA) NM_002096 NM_133801 RefSeq (protein) NP_002087 NP_598562 Location (UCSC) Chr 19: 6.38 – 6.39 Mb Chr 17: 57.31 – 57.32 Mb PubMed search
Wikidata
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General transcription factor IIF subunit 1 is a protein that in humans is encoded by the GTF2F1 gene.