GPRC6A

GPRC6A
Identifiers
Aliases	GPRC6A, GPCR, bA86F4.3, G protein-coupled receptor class C group 6 member A
External IDs	OMIM: 613572; MGI: 2429498; GeneCards: GPRC6A
Gene location (Human)
Chr.	Chromosome 6 (human)
End	116,829,083 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	51,507,557 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; salivary gland; ; minor salivary glands; ; islet of Langerhans; ; human kidney; ; right adrenal gland; ; right adrenal cortex; ; muscle of thigh; ; left adrenal gland;
	Top expressed in
	embryo; ; embryo; ; left lung lobe; ; right lung lobe; ; islet of Langerhans;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; signaling receptor activity;
Cellular component	integral component of membrane; cell surface; plasma membrane; intracellular anatomical structure; membrane; integral component of plasma membrane;
Biological process	response to amino acid; calcium-mediated signaling; signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	222545
	210198
	ENSG00000173612
	ENSMUSG00000019905
	Q5T6X5
	Q8K4Z6
	NM_148963; NM_001286354; NM_001286355
	NM_153071
	NP_001273283; NP_001273284; NP_683766
	NP_694711
	Wikidata
View/Edit Human	View/Edit Mouse

G protein-coupled receptor family C group 6 member A (GPRC6A) is a protein that in humans is encoded by the GPRC6A gene. This protein functions as a receptor of L-α-amino acids, cations (e.g., calcium), and osteocalcin. It has also been found to mediate some of the effects of testosterone, but the direct affinity with the receptor is relative low, so the precise mechanism remains controversial.