Complement factor B

CFB
Identifiers
Aliases	CFB, Cfb, AI195813, AI255840, Bf, C2, Fb, H2-Bf, AHUS4, ARMD14, BFD, CFAB, CFBD, FBI12, GBG, PBF2, complement factor B
External IDs	OMIM: 138470; MGI: 105975; GeneCards: CFB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3HS0, 1DLE, 1Q0P, 1RRK, 1RS0, 1RTK, 2OK5, 2WIN, 2XWB, 2XWJ, 3HRZ
Enzyme activity
Gene location (Human)
Chr.	Chromosome 6 (human)
End	31,952,084 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	35,081,494 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; gallbladder; ; appendix; ; duodenum; ; islet of Langerhans; ; olfactory zone of nasal mucosa; ; Descending thoracic aorta; ; gastric mucosa; ; right coronary artery; ; human kidney;
	Top expressed in
	proximal tubule; ; right kidney; ; human kidney; ; white adipose tissue; ; hepatobiliary system; ; liver; ; jejunum; ; ileum; ; colon; ; duodenum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	peptidase activity; serine-type peptidase activity; serine-type endopeptidase activity; hydrolase activity; complement binding; protein binding;
Cellular component	extracellular region; plasma membrane; blood microparticle; extracellular exosome; extracellular space;
Biological process	complement activation; regulation of complement activation; proteolysis; immune system process; complement activation, alternative pathway; innate immune response;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	629
	14962
ENSG00000243570; ENSG00000239754; ENSG00000243649; ENSG00000241253; ENSG00000242335;
	ENSG00000241534; ENSG00000204359
	ENSMUSG00000090231
	P00751
	P04186
	NM_001710
	NM_001142706; NM_008198
	NP_001701
	NP_001136178; NP_032224; NP_001389804
	Wikidata
View/Edit Human	View/Edit Mouse

Complement factor B is a protein that in humans is encoded by the CFB gene.