Recurrent cancer

Recurrent cancer is any form of cancer that has returned or recurred when a fraction of primary tumor cells evade the effects of treatment and survive in small spaces that are undetectable by diagnostic tests. If recurrent cancer has already moved to other body parts or has developed chemo-resistance then it may be more aggressive than original cancer. In general, the severity of cancer increases with a shorter duration of time between initial treatment and its return.

Cancers with the highest recurrence rates include Glioblastoma with a recurrence rate of almost 100%, Epithelial ovarian cancer with a recurrence rate of 85%, and Bladder cancer with a recurrence rate of 30–54%