CD68

CD68
Identifiers
Aliases	CD68, GP110, LAMP4, SCARD1, CD68 molecule
External IDs	OMIM: 153634; MGI: 88342; GeneCards: CD68
Gene location (Human) Chr. Chromosome 17 (human) Band 17p13.1 Start 7,579,491 bp End 7,582,111 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11 B3|11 42.86 cM Start 69,555,039 bp End 69,556,979 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in white blood cell monocyte granulocyte duodenum appendix stromal cell of endometrium gallbladder placenta right lung lymph node Top expressed in stroma of bone marrow calvaria decidua granulocyte spleen body of femur ankle tibiofemoral joint right lung lobe mesenteric lymph nodes More reference expression data BioGPS n/a
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 968 12514 Ensembl ENSG00000129226 ENSMUSG00000018774 UniProt P34810 P31996 RefSeq (mRNA) NM_001251 NM_001040059 NM_001291058 NM_009853 RefSeq (protein) NP_001035148 NP_001242 NP_001277987 Location (UCSC) Chr 17: 7.58 – 7.58 Mb Chr 11: 69.56 – 69.56 Mb PubMed search
Wikidata
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CD68 immunostaining demonstrating macrophages and giant cells in a case of xanthogranulomatous pyelonephritis

CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia).