CD20

MS4A1
Identifiers
Aliases	MS4A1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7, membrane spanning 4-domains A1, FMC7
External IDs	OMIM: 112210; MGI: 88321; GeneCards: MS4A1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3PP4, 2OSL, 3BKY
Gene location (Human)
Chr.	Chromosome 11 (human)
End	60,470,752 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	11,243,605 bp
RNA expression pattern
	Top expressed in
	epithelium of nasopharynx; ; spleen; ; lymph node; ; mucosa of ileum; ; appendix; ; granulocyte; ; blood; ; tonsil; ; bone marrow; ; superficial temporal artery;
	Top expressed in
	mesenteric lymph nodes; ; spleen; ; blood; ; oocyte; ; primary oocyte; ; submandibular gland; ; tibiofemoral joint; ; secondary oocyte; ; zygote; ; Ileal epithelium;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	epidermal growth factor receptor binding; protein binding; MHC class II protein complex binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; extracellular exosome; membrane; external side of plasma membrane; extracellular space; nucleus;
Biological process	B cell activation; B cell proliferation; humoral immune response; response to bacterium;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	931
	12482
	ENSG00000156738
	ENSMUSG00000024673
	P11836
	P19437
	NM_152866; NM_021950; NM_152867
	NM_007641
	NP_068769; NP_690605; NP_690606
	NP_031667
	Wikidata
View/Edit Human	View/Edit Mouse

B-lymphocyte antigen CD20 or CD20 is B lymphocyte cell-surface molecule.

It is a 33-37 kDa non-glycosylated protein. CD20 is expressed on the surface of B-cells from the pre-B phase, the expression is lost in terminally differentiated plasma cells.

CD20 is used as a therapeutical target of B-cell malignancies and autoimmune diseases.