C4A

C4A
Identifiers
Aliases	C4A, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, complement component 4A (Rodgers blood group), complement C4A (Rodgers blood group)
External IDs	OMIM: 120810; MGI: 88228; GeneCards: C4A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1HZF, 4FXG, 4FXK, 4XAM
Gene location (Human)
Chr.	Chromosome 6 (human)
End	32,002,681 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,962,856 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; right adrenal cortex; ; left adrenal cortex; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; right ovary; ; tibial nerve; ; left ovary; ; anterior pituitary; ; spleen;
	Top expressed in
	zone of skin; ; adrenal gland; ; white adipose tissue; ; synovial joint; ; ankle joint; ; spleen; ; liver; ; uterus; ; esophagus; ; urinary bladder;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	endopeptidase inhibitor activity; complement component C1q complex binding; serine-type endopeptidase activity;
Cellular component	extracellular region; plasma membrane; extracellular exosome; blood microparticle; cell projection; dendrite; cell junction; synapse; axon; soma; extracellular space; endoplasmic reticulum lumen;
Biological process	complement activation; inflammatory response; positive regulation of apoptotic cell clearance; regulation of complement activation; negative regulation of endopeptidase activity; complement activation, classical pathway; immune system process; innate immune response; proteolysis; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	720
	12268
	ENSG00000244207; ENSG00000206340; ENSG00000244731; ENSG00000227746
	ENSMUSG00000073418
	P0C0L4
	P01029
	NM_001252204; NM_007293
	NM_009780
	NP_001239133; NP_009224
	NP_033910
	Wikidata
View/Edit Human	View/Edit Mouse

Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene.