Ankyrin-1

ANK1
Identifiers
Aliases	ANK1, ANK, SPH1, SPH2, ankyrin 1
External IDs	OMIM: 612641; MGI: 88024; GeneCards: ANK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N11, 2YQF, 2YVI, 3F59, 3KBT, 3KBU, 3UD1, 3UD2
Gene location (Human)
Chr.	Chromosome 8 (human)
End	41,896,762 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	23,640,513 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle; ; body of tongue; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; muscle of thigh; ; thoracic diaphragm; ; apex of heart; ; glutes; ; gastrocnemius muscle;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; muscle of thigh; ; inferior colliculi; ; lobe of cerebellum; ; triceps brachii muscle; ; vastus lateralis muscle; ; pontine nuclei; ; cerebellar vermis; ; sternocleidomastoid muscle; ; skeletal muscle tissue;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	spectrin binding; ATPase binding; structural molecule activity; structural constituent of cytoskeleton; protein binding; enzyme binding; cytoskeletal anchor activity;
Cellular component	M band; cytosol; postsynaptic membrane; membrane; plasma membrane; sarcoplasmic reticulum; basolateral plasma membrane; Z discdkac; axolemma; spectrin-associated cytoskeleton; neuron projection; sarcolemma; A band; cytoskeleton; nucleus; cytoplasm;
Biological process	positive regulation of organelle organization; endoplasmic reticulum to Golgi vesicle-mediated transport; maintenance of epithelial cell apical/basal polarity; cytoskeleton organization; signal transduction; exocytosis; protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	286
	11733
	ENSG00000029534
	ENSMUSG00000031543
	P16157
	Q02357
NM_000037; NM_001142445; NM_001142446; NM_020475; NM_020476;
	NM_020477; NM_020478; NM_020479; NM_020480; NM_020481
NM_001110783; NM_001277280; NM_001277281; NM_001277284; NM_001277286;
	NM_001277289; NM_031158; NM_001310436; NM_001310437
NP_000028; NP_001135917; NP_001135918; NP_065208; NP_065209;
	NP_065210; NP_065211; NP_065213
NP_001104253; NP_001264209; NP_001264210; NP_001264213; NP_001264215;
	NP_001264218; NP_001297365; NP_001297366; NP_112435
	Wikidata
View/Edit Human	View/Edit Mouse

Ankyrin 1, also known as ANK-1, and erythrocyte ankyrin, is a protein that in humans is encoded by the ANK1 gene.