ADAMTS1

ADAMTS1
Identifiers
Aliases	ADAMTS1, C3-C5, METH1, ADAM metallopeptidase with thrombospondin type 1 motif 1
External IDs	OMIM: 605174; MGI: 109249; GeneCards: ADAMTS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JIH, 2V4B, 3Q2G, 3Q2H
Gene location (Human)
Chr.	Chromosome 21 (human)
End	26,845,409 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	85,600,001 bp
RNA expression pattern
	Top expressed in
	right ovary; ; left uterine tube; ; vena cava; ; left ovary; ; pericardium; ; gastric mucosa; ; decidua; ; tibial arteries; ; mucosa of urinary bladder; ; ascending aorta;
	Top expressed in
	iris; ; left lung lobe; ; efferent ductule; ; stroma of bone marrow; ; ciliary body; ; gastrula; ; ascending aorta; ; aortic valve; ; vas deferens; ; decidua;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	heparin binding; zinc ion binding; metal ion binding; peptidase activity; metalloendopeptidase activity; hydrolase activity; metallopeptidase activity;
Cellular component	extracellular region; basement membrane; cytoplasmic vesicle; extracellular matrix; collagen-containing extracellular matrix;
Biological process	ovulation from ovarian follicle; heart trabecula formation; kidney development; proteolysis; integrin-mediated signaling pathway; negative regulation of cell population proliferation; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of vascular associated smooth muscle cell proliferation; positive regulation of vascular associated smooth muscle cell migration;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	9510
	11504
	ENSG00000154734
	ENSMUSG00000022893
	Q9UHI8
	P97857
	NM_006988
	NM_009621
	NP_008919
	NP_033751
	Wikidata
View/Edit Human	View/Edit Mouse

A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene.